NuclearQuant module

NuclearQuant is a tool for fast and robust IHC nuclear analysis.


NuclearQuant performs automatic evaluation on IHC nuclear stainings (ER, PR, Ki67, P53, etc). Using color deconvolution, NuclearQuant detects cell nuclei and measures staining intensity on the chromogen channel. This way it is possible to calibrate the software to the actual stain protocol in the pathology lab. The algorithm categorizes the detected nuclei to negative, weak positive, medium positive and strong positive classes.

This software has an IVD certification for Estrogen (ER) and Progesterone (PR) quantification.

Linkable module concept: Run PatternQuant or HistoQuant for tissue pre-segmentation first to get more precise results and to speed up the cell based measurement. A whole digital slide can be analyzed in a matter of minutes.


Other features:

  • Powerful gallery with re-scoring and co-localization function
  • Batch processing
  • Excel data export
  • Histogram, pie chart, scatterplot visualization options
  • Reporting


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QuantCenter is the framework for 3DHISTECH image analysis applications

HistoQuant module

HistoQuant detects regions of interest based on the color and intensity information.